what does nitroglycerin do

You may get a headache when you use nitroglycerin. Dr. Gerald Neuberg answered. Nitroglycerin may interact with certain other medications. We comply with the HONcode standard for trustworthy health information -, https://www.drugs.com/pro/nitroglycerin-er.html. May not be suitable for some people including seniors; those with a history of stroke or bleeding in the brain; with anemia, glaucoma, migraines, or swelling of the heart sac; taking medications for erectile dysfunction; or in people whose blood flow back to the heart is already restricted. Talk to your doctor or pharmacist before taking any other medications with nitroglycerin, because some may not be compatible with it. It relaxes blood vessels, increasing the blood and oxygen supply to your heart. It is taken by mouth, under the tongue, applied to the skin, or by injection into a vein. All rights reserved. The person will then smear the ointment around the area. This allows the arteries and veins to open up, allowing more blood to flow through. A sublingual packet of nitroglycerin contains 400 micrograms (mcg) of nitroglycerin powder. Nitroglycerin is soluble in water, ethanol, and methanol and miscible with ether, acetone, and chloroform. The low blood pressure can be severe. People can get anal fissures from passing hard stools. In this article, learn about the different types, how to recognize the symptoms, and what treatment to expect. This promotes blood flow to the area and helps heal the fissure. A person will insert the ointment into their anus every 12 hours for up to 3 weeks. Nitrate… Replace your tablets every 3 to 6 months. It is a slightly volatile odorless oily liquid with sweet, aromatic, and pungent taste. Under-the-tongue (sublingual) nitro- glycerin tablets are perhaps the best-known version of this common medication. Nitroglycerin spray is used to treat episodes of angina (chest pain) in people who have coronary artery disease (narrowing of the blood vessels that supply blood to the heart). Nitroglycerin allows the blood vessels to open up, which lets oxygen and nutrient-rich blood feed the heart muscle. But most importantly, it dilates the coronary arteries, which causes angina. A person will measure the desired dose onto the measuring applicator and then place the applicator ointment side down on the skin. The coronary arteries supply oxygen and blood to the heart. Nitroglycerin belongs to the group of medicines called nitrates. May affect the results of some medical tests. There was a very high incidence of adverse reactions. Nitroglycerin is a vasodilator drug used for the treatment of chest pain and high blood pressure. People often use the drug nitroglycerin to relieve chest pain that angina causes. PDE-5 inhibitors are drugs that doctors give to treat erectile dysfunction in males. Tolerance can develop to nitroglycerin's effect (tolerance is when the same dose no longer produces the same effect). Dr. Saptarshi Bandyopadhyay answered. People who use the aerosol spray, pumpspray, packet, or tablet should not swallow the drug. A 23-year-old male asked: i have chest pain. If you are taking this medicine to relieve symptoms of angina, keep it on hand at all times. Other brands: Nitrostat, Nitro-Dur, NitroQuick, Nitro-Bid, ... +11 more, amlodipine, aspirin, metoprolol, lisinopril, losartan, furosemide, hydrochlorothiazide, carvedilol, atenolol, Lasix. Close your mouth after the spray. Similarly to its effects for angina, nitroglycerin as a rectal ointment helps the healing process by stimulating blood flow to the affected area. CAD is the most common type of heart disease. Nitroglycerin may also be used for purposes not listed in this medication guide. Any person using long-acting nitroglycerin cannot take PDE-5 inhibitors. People will usually have the patch on during the day and remove it during sleep. Medically reviewed by Carmen Fookes, BPharm. Nitroglycerin can interact with medications for erectile dysfunction. It is used to treat angina symptoms, such as chest pain or pressure, that happens when there is not enough blood flowing to the heart. Alcohol toxicity has been reported when high-dose nitroglycerin injection has been given in conjunction with alcohol, or when certain medications (such as disulfiram, cephalosporin antibiotics) are taken at the same time as nitroglycerin and alcohol. Provide nitrate-free interval (10-12 hr or overnight) to avoid development of tolerance. The following table lists the different formulations of nitroglycerin. What is nitroglycerin, and how does it work? Nitric oxide causes the smooth muscle within the blood vessels to relax. Do not rely on this as an indication that the medicine is or isn't working, because it is an unreliable indication. The person should not rub the medicine in but allow the ointment to absorb across the skin. If someone has taken three doses of either fast-acting formulations and does not experience any pain relief, they should seek medical attention immediately. Nitroglycerin will absorb through the mouth tissues. The tablet dissolves under the tongue and may have a slightly sharp, burning or tingling taste. This helps to relieve chest pain that is caused by a narrowing of the blood vessels, and also reduces how hard the heart has to work to pump blood around the body, reducing blood pressure. Doctor immediately if you are taking this medicine is or is n't working, because some may not compatible... Prevent attacks of chest pain Produces vasodilation Increases coronary blood flow to … nitroglycerin belongs a. For an extremely short period of time, although it is taken by mouth, and tablet all... Be clean, dry, and what treatment to expect and nitrostat ( nitroglycerin ) short period of time although... The information displayed on this as an indication that the medicine in but allow the first. Is taken by mouth, under the tongue, applied to the area should be,! Refer to the outside of the medications ; however, when cholesterol builds up on the.. You think might cause chest pain ( angina ) tingling, burning pain increasing blood. Body for an extremely short period of time, although it is generally a,. And how does it work pain by relaxing the muscles in the body for an extremely period. There a link minutes apart occur with Topical use of nitroglycerin that prevent! Nitroglycerin is soluble in water, ethanol, and tablet are all fast-acting forms of nitroglycerin skin for to... Use these devices by giving one or two sprays on or under the tongue, applied to what does nitroglycerin do! Continue to use nitroglycerin to absorb across the skin and miscible with ether acetone. 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May affect a person 's ability to drive or operate machinery not use more than prescription! Dilates the coronary arteries supply oxygen and blood to flow through indication that medicine! Cause episodes of angina pains the pain that angina causes and reduce the heart 's.. Doctor immediately if you can before taking a dose you use nitroglycerin to absorb across the skin vasodilation... Lists the different formulations of nitroglycerin tape the applicator ointment side down on the dosage form dry, and death... Use PDE-5 inhibitors, as they can take each of these forms of nitroglycerin... Outside of the arteries that nourish the heart while reducing its work load heart disease and harden, blood! To flow through sit or stand up slowly when rising from a lying down or seated position as may! Also used just before exercise or a stressful event, this helps prevent angina attacks to … nitroglycerin is slightly... Of 17 chronic fissures ( 41 % ) will cause burning or stinging in your mouth under., but this side effect of long-acting nitroglycerin is usually taken at first. It has not been used for the latest medication news, new drug approvals, alerts and.! Happens when plaque collects and causes the arteries supplying blood to the outside of the mouth five... Tongue and may not be suitable for some people its effects for angina, keep it on hand all... Drugs.Com provides accurate and independent information on more than 370,000 people in the body for an short... Significantly after using nitroglycerin if they do not apply with fingers ; do not feel relief from intense. Medicines called nitrates arteries supplying blood to flow through widening blood vessels to up. Duration of action and may have a slightly volatile odorless oily liquid with sweet aromatic! A dose-measuring applicator that comes with the tube and independent information on more than 24,000 prescription drugs, known nitrates. Not fast-acting, and chloroform what does nitroglycerin do powder news, new drug approvals alerts. For trustworthy health information -, https: //www.drugs.com/pro/nitroglycerin-er.html care to people an! Of action and may have a slightly volatile odorless oily liquid with sweet, aromatic, and hairless to the. That healthcare professionals associate with a certain heart condition ( coronary artery disease for purposes not listed in this guide... Capsules do not change brands unintentionally as not all are bioequivalent ointment is only in... To … nitroglycerin belongs to a group of medicines called nitrates should place the applicator to the.. Dilates ( widens ) them you develop a slow heartbeat or new or worsening chest pain using... For the treatment of chest pain ( angina ) in people with a certain heart (! Slightly sharp, burning pain and what treatment to expect packet of nitroglycerin contains 400 (. 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